Blood Flow in Dissected Aortas After Thoracic Endovascular Aortic Repair

Examensarbete för masterexamen

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Bibliographical item details
Type: Examensarbete för masterexamen
Title: Blood Flow in Dissected Aortas After Thoracic Endovascular Aortic Repair
Authors: Subramaniasivam, Vishal
Abstract: Every passing hour, 2050 people die due to cardiovascular diseases, a third of them occurring prematurely before the age of 70. An aortic dissection is a condition where a sudden tear in the aortic wall forces blood to enter between the layers of the wall, subsequently splitting the wall and creating a new channel for blood. Untreated aortic dissections have a mortality rate of 80% at two weeks from the initial tear and treated aortic dissections have a mortality rate of 40% at five years. One treatment option is Thoracic Endovascular Aortic Repair (TEVAR), which involves placing one or several implants known as stent-grafts or endografts on the inner surface of the aorta. About 38% of TEVAR procedures come with post-procedural complications and approximately 19% to 24% require secondary re-interventions. Computational fluid dynamics (CFD) simulations can be used as a tool to predict post-procedural complications from a fluid mechanical perspective. In this study, the comparison of two post-surgical lumen scenarios is reported by conducting blood simulations using OpenFOAM, an open-source CFD tool. A study is also done on the non-Newtonian nature of blood and results are reported on the influence of using a non-Newtonian viscosity model as opposed to a Newtonian (constant viscosity) model. Validation of the computational grid and the viscosity model is done against experimental results retrieved from another study that used porcine blood.
Keywords: aorta;blood;non-Newtonian;viscosity;wall shear stress;TEVAR;OpenFOAM;vorticity;dissections;shear-thinning
Issue Date: 2021
Publisher: Chalmers tekniska högskola / Institutionen för mekanik och maritima vetenskaper
Series/Report no.: 2021:67
Collection:Examensarbeten för masterexamen // Master Theses

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