Development of a triboelectrically powered intracranial pressure sensor and a brain phantom test rig
Typ
Examensarbete för masterexamen
Master's Thesis
Master's Thesis
Program
Biotechnology (MPBIO), MSc
Publicerad
2023
Författare
Afshar, Shabir
Modellbyggare
Tidskriftstitel
ISSN
Volymtitel
Utgivare
Sammanfattning
Intracranial pressure (ICP) monitoring is crucial for diagnosing and treating
neurological disorders. This master thesis focuses on developing a self-powered
pressure sensor for wireless pressure monitoring inside the skull. The sensor
design is based on triboelectric technology, aiming to overcome the limitations
of conventional ICP sensors such as power supply requirements, complex
fabrication, and mechanical inflexibility.
The primary goal of this study is to explore the potential of triboelectric
pressure sensors for monitoring ICP. A test rig and brain phantom are also
constructed to simulate pressure variations of the actual brain in vitro.
Triboelectric sensors convert mechanical pressure into electrical signals
through electrostatic induction. First, the literature is reviewed on ICP and
conventional invasive pressure sensors. Then, simulations of the modelled
sensor are conducted by COMSOL software. Achieved results provide valuable
insights into the implementation and feasibility of triboelectric pressure sensors
for ICP monitoring. Additionally, the project successfully achieved the
construction of a simplified brain phantom with a pressure-tight ventricle void.
This was accomplished by casting silicone rubber into a 3D-printed mould,
serving as the project’s secondary goal.
In conclusion, this thesis presents extensive research on developing and
evaluating triboelectric sensing mechanisms for ICP monitoring. The findings
contribute to the advancement of less invasive pressure sensors, holding
potential significance in neurology and healthcare.
Beskrivning
Ämne/nyckelord
Intracranial pressure, self-powered sensors, bio-compatible implantable sensors, triboelectrification, Brian phantom