Blood Flow in Dissected Aortas After Thoracic Endovascular Aortic Repair
| dc.contributor.author | Subramaniasivam, Vishal | |
| dc.contributor.department | Chalmers tekniska högskola / Institutionen för mekanik och maritima vetenskaper | sv |
| dc.contributor.examiner | Nilsson, Håkan | |
| dc.contributor.supervisor | Nilsson, Håkan | |
| dc.contributor.supervisor | Bondesson, Johan | |
| dc.date.accessioned | 2021-09-09T12:50:48Z | |
| dc.date.available | 2021-09-09T12:50:48Z | |
| dc.date.issued | 2021 | sv |
| dc.date.submitted | 2020 | |
| dc.description.abstract | Every passing hour, 2050 people die due to cardiovascular diseases, a third of them occurring prematurely before the age of 70. An aortic dissection is a condition where a sudden tear in the aortic wall forces blood to enter between the layers of the wall, subsequently splitting the wall and creating a new channel for blood. Untreated aortic dissections have a mortality rate of 80% at two weeks from the initial tear and treated aortic dissections have a mortality rate of 40% at five years. One treatment option is Thoracic Endovascular Aortic Repair (TEVAR), which involves placing one or several implants known as stent-grafts or endografts on the inner surface of the aorta. About 38% of TEVAR procedures come with post-procedural complications and approximately 19% to 24% require secondary re-interventions. Computational fluid dynamics (CFD) simulations can be used as a tool to predict post-procedural complications from a fluid mechanical perspective. In this study, the comparison of two post-surgical lumen scenarios is reported by conducting blood simulations using OpenFOAM, an open-source CFD tool. A study is also done on the non-Newtonian nature of blood and results are reported on the influence of using a non-Newtonian viscosity model as opposed to a Newtonian (constant viscosity) model. Validation of the computational grid and the viscosity model is done against experimental results retrieved from another study that used porcine blood. | sv |
| dc.identifier.coursecode | MMSX30 | sv |
| dc.identifier.uri | https://hdl.handle.net/20.500.12380/304099 | |
| dc.language.iso | eng | sv |
| dc.relation.ispartofseries | 2021:67 | sv |
| dc.setspec.uppsok | Technology | |
| dc.subject | aorta | sv |
| dc.subject | blood | sv |
| dc.subject | non-Newtonian | sv |
| dc.subject | viscosity | sv |
| dc.subject | wall shear stress | sv |
| dc.subject | TEVAR | sv |
| dc.subject | OpenFOAM | sv |
| dc.subject | vorticity | sv |
| dc.subject | dissections | sv |
| dc.subject | shear-thinning | sv |
| dc.title | Blood Flow in Dissected Aortas After Thoracic Endovascular Aortic Repair | sv |
| dc.type.degree | Examensarbete för masterexamen | sv |
| dc.type.uppsok | H | |
| local.programme | Applied mechanics (MPAME), MSc |