Computational Modeling of Cardiac Shockwave Therapy with Piezoelectric Transducers
Typ
Examensarbete för masterexamen
Master's Thesis
Master's Thesis
Program
Complex adaptive systems (MPCAS), MSc
Publicerad
2024
Författare
de Wilde, Willem
Modellbyggare
Tidskriftstitel
ISSN
Volymtitel
Utgivare
Sammanfattning
Cardiac shockwave therapy (CSWT) has emerged as a promising treatment for ischemic
heart disease, offering non-invasive rehabilitation options for patients suffering
from myocardial infarction and refractory angina pectoris. This thesis focuses
on developing a computational model to simulate the generation and propagation of
acoustic waves associated with CSWT, emphasizing the role of piezoelectric transducers.
Utilizing COMSOL Multiphysics, several models were implemented, including
two-dimensional axisymmetric and one-dimensional plane wave propagation
models, based on the nonlinear time explicit acoustic physics interface. The study
also explores the design and simulation of piezoelectric transducers. Coupled simulations
which model both piezoelectric transducers and acoustic propagation in
biological tissue were implemented. Complex three-dimensional anatomical geometries
were constructed, though not simulated. The numerical methods developed
provide insights into the acoustic behavior of shockwaves within tissues, though
experimental validation remains pending. This research contributes to the advancement
of CSWT technology, potentially facilitating the development of a wearable
device for self-administered CSWT.
Beskrivning
Ämne/nyckelord
Cardiac Shockwave Therapy , COMSOL , Multiphysics , Computational Acoustics , Nonlinear Acoustics , Piezoelectric Shockwave Transducer