Computational Modeling of Cardiac Shockwave Therapy with Piezoelectric Transducers

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dc.contributor.authorde Wilde, Willem
dc.contributor.departmentChalmers tekniska högskola / Institutionen för mekanik och maritima vetenskapersv
dc.contributor.departmentChalmers University of Technology / Department of Mechanics and Maritime Sciencesen
dc.contributor.examinerFolkow, Peter
dc.contributor.supervisorStaaf, Henrik
dc.contributor.supervisorRusu, Cristina
dc.date.accessioned2024-08-20T13:39:46Z
dc.date.available2024-08-20T13:39:46Z
dc.date.issued2024
dc.date.submitted
dc.description.abstractCardiac shockwave therapy (CSWT) has emerged as a promising treatment for ischemic heart disease, offering non-invasive rehabilitation options for patients suffering from myocardial infarction and refractory angina pectoris. This thesis focuses on developing a computational model to simulate the generation and propagation of acoustic waves associated with CSWT, emphasizing the role of piezoelectric transducers. Utilizing COMSOL Multiphysics, several models were implemented, including two-dimensional axisymmetric and one-dimensional plane wave propagation models, based on the nonlinear time explicit acoustic physics interface. The study also explores the design and simulation of piezoelectric transducers. Coupled simulations which model both piezoelectric transducers and acoustic propagation in biological tissue were implemented. Complex three-dimensional anatomical geometries were constructed, though not simulated. The numerical methods developed provide insights into the acoustic behavior of shockwaves within tissues, though experimental validation remains pending. This research contributes to the advancement of CSWT technology, potentially facilitating the development of a wearable device for self-administered CSWT.
dc.identifier.coursecodeMMSX30
dc.identifier.urihttp://hdl.handle.net/20.500.12380/308442
dc.language.isoeng
dc.setspec.uppsokTechnology
dc.subjectCardiac Shockwave Therapy
dc.subjectCOMSOL
dc.subjectMultiphysics
dc.subjectComputational Acoustics
dc.subjectNonlinear Acoustics
dc.subjectPiezoelectric Shockwave Transducer
dc.titleComputational Modeling of Cardiac Shockwave Therapy with Piezoelectric Transducers
dc.type.degreeExamensarbete för masterexamensv
dc.type.degreeMaster's Thesisen
dc.type.uppsokH
local.programmeComplex adaptive systems (MPCAS), MSc
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